Daniel Day Lewis(has made 10 movies total, 3 Oscar Noms. phenomenal in last 3 films, need I say more)
Bill Murray (probably has the best range, next to J Depp)
John Tuturo (name a good movie, he's in it)
George Clooney(lots of range, Roseanne, can direct and write as well)
Ian McKellan(can't dispute, he's what Peter O'Toole could have been)