For me I see things as this in terms of rotation:
Vidal (Asamoah)
Pirlo (Marrone)
Marchisio (Pogba/Asamoah)
Giach, Paz, Pad...providing all stay shouldn't play ahead of Marrone. Besides, we have yet to see what Pogba can actually do. Isla was brought for width, I doubt we will see him as a CM.
---------- Post added 23.07.2012 at 11:38 ----------
On top of that, just because one starts the game doesn't mean they will always play the full 90 mins...there will be plenty of time to get some PT in there as well as a sub plus a some starts to rest the key players.