I'd rest Buffon, Zanetti, Chiellini, Camoranesi and Nedved. These are nothing games now anyway. Winning both or losing both does nothing to the standings.
I'd field something like this:
------------------Belardi
Zebina-Stendardo-Legrottaglie-Grygera
--Iaquinta-Tiago-Sissoko-Salihamidzic
------------Del Piero-Trezeguet
Palladino would be a guaranteed substitute at offense. I'd also call up a couple primavera players for a look.