I'm ok with Afflek, he is safe and boring choice, but I'm ok with it, he or whoever they would have casted would be automatic failure compared to Bale anyways. he should do decent enough job as Bruce Wayne, remains to be seen if he is competent enough for the Bat scenes (I fail to see how he will be remotely gritty and dark enough for Batman, but then again I think the directors will fail at this part regardless of casting choice).
But Jesse, though he does the smartass upstaging crooked kinda thing well, I have hard time seeing being an evil menacing villain. Intelligence part of Lex he will potray well enough I think, but doubt he can be threatening enough. But hope he suprises me, generally find his scthtick fairly amusing, now lets see him add some darkness to it.