Creatine
1) Intro
When the muscle contracts, it requires energy. This energy is provided by breaking down ATP(adenosinetriphospate) into ADP (adenosinediphosphate). The body can only store enough ATP molecules for less then 2 seconds.
However, the muscle cells can store creatine in the so called 'creatine deposits'. When the muscle contracts and ATP is depleted, creatine will quickly be broken down into creatinine. The released energy is used to regenerate ADP into ATP.
While all that happens, the slower proces of breaking down muscular glycogene happens on the background to provide continious energy for creatinine to regenerate into creatine.
2) Creatine deposits
If you are a vegeratian assfuck, your deposits will be half their maximum fill. Supplementing creatine monohydrate (5g/day) or buffered (2.3g/day) for about 2-3 weeks should max out your deposits
If you eat meat, your deposits will be 3/4 filled
If you frequently eat red meat, your creatine deposits will be maxed out by defauld, because red meat is the source of all power. Eat low fat (2% or less) .
3) effects of creatine supplementation
- filling up deposits in the muscle. This is why they advertise you will train harder, longer, better. Its purely related to the fill of the deposits.
- 'water retention'. This happens but has such little effect that it shouldnt be mentionned.
4) Does creatine fuck up the liver ?
No.
5) But the label says i need to drink enough water
You are a fucking peasant shitfuck if you dont drink enough water. Drink at least 2 liters per day.
If you arent drinking enough water, you will strain your kidneys with anything you eat, you will fuck up anti inflammatory response, you will fuck up your recovery, and you will fuck up your strenght. DRINK THE WATER.
6) But if the promises on the label are false, what can i buy that do exactly what creatine claims to be doing (anabolic growth, stronger muscles)
Aromatising steroids.
THAT will fuck up your liver.
7) What is the effect of actual water retention (seriously ford, you should know this)
Water retention in the muscles is determined by osmose, so it depends on the dissolved substance concentration. Aka, muscular glycogene. On aromatising steroids, this can be significantly increased.
Water retention in the muscles proved a direct and strong increase in power of the muscle. Not the tendon however, meaning you'll tear it faster.
8) why is the water retention story by creatine full of shit ?
Creatine draws more water in the veigns. Not the muscle.
When a muscle faces microtrauma, macrophages will start to devour the muscular debris of the trauma. They will secrate a bunch of stuff. One of those is signalisating molecules for the RTK, the other are histamines for example.
RTK (receptor tyrosine kinase) is a monomere that has 3 unloaded tyrosine's and one receptor place. When a signaling molecule(secreted from macrophage devouring muscle debris,95 identified so far) binds to the receptor of the RTK, it will activate and bind with another activated monomere, and form an activated RTK dimer. 6 ATP are used to turn it into a loaded, activated RTK. This will now bound to the IFG-1 (insuline like growth factor one) and activate the hormone. This hormone will activate the ATK pathway and protein synthesis will start.
Meanwhile, histamines secreted from the macrophages will start to vascodilate the muscle (blood vessels remain open for longer). This is 'muscle pump'. More blood will be drawn into the muscle. more moisture also. because of the opening of blood vessels, proteins travelling trough the veigns will stay in the blood vessels for longer. As a result of osmosis, more water will be drawn into the cell, creating slight swelling. This is the visual effect of muscle pump.
Also meanwhile, because of microtrauma, calcium formerly retained by the smooth endoplasmatic reticulum, will be concentrated freely between the debris. This will draw specific White blood cells to activate and attack smaller debris. This will increase inflammation. (this specific WBC reaction is countered by taking non steroidal anti inflammatory drugs (NSAID))
This is a natural proces. Creatine does jack shit to increase it. Steroids significantly increase the opening time of blood vessels which allow a MUCH longer anabolic window.
10) So what do i do with my money
- eat 2+grams of quality protein per kilogram of bodyweight. quality protein means it comes from meat or protein powder/bar.
- eat complex sugar (potatoe,rice,pasta, oat, whole-wheat grains)
- take 150-500mg of cafeine 15 minutes before training, depending on tolerance
- take a multivitamin supplement. Vitamins are vital for hormonal function.