I think it would be easier for him and us if that first leg is at home again. Looking at the fixture list as it stands:
23/4 Genoa (H)
29/4 Atalanta (A)
2-3/5 SF1
06/5 Torino (H)
9-10/5 SF2
14/5 Roma (A)
Those games are sandwiched between a difficult bunch, that derby could be a real spanner in the works. By the time we play Roma it would be nice to have the job almost done. Marchisio could do with getting the last half an hour of the Atalanta game, otherwise he's going to go into that semi final cold considering he probably won't be fit for Genoa.
Juve have to change up if Marchisio can't make the semi, Rincon ends up becoming an authentic DM and Pjanic has to play a little further forward. The other unlikely option is Lemina, but he's too stupid to be expected to play Khedira's role with any competence.