This guy 
Seriously Dukac, i'm gonna try to explain the situation again, please read this carefully, cause you are wrongly interpreting it.
When you exercise, you create microtrauma in the muscles, tendons and ligaments. The body has a natural response to recover from this. Because of structural differences, the natural recovery of tendons&ligaments, versus muscles is completely different in speed and mechanism.
Muscles :
Tendons and ligaments :
As seen in the spoilored explenations above, muscles, ligaments and tendons that recover naturally from training, will be slightly inflammated, and in tendons this can build up. This inflammation will decrease the natural recovery from training. When taking NSAID's, this inflammation caused by training will be kept on a minimum, so the natural recovery will be at its best speed.
When you tear something, it will take 4-6 months to recover. However, the recovery system works in the same way. First the ligament or tendon is reattached. step 1(see second spoiler) will clean up all necrotic tissue, causing inflammation. THis step occurs in the hospital, so the patient will receive intravenous NSAID's to controll this . Once past the worst inflammation response (your knee is swollen as fuck), you can go home and will be prescribed with oral NSAID's for some weeks. After x weeks, a docter will examine your scar tissue. In step 2(see second spoiler), we see the collagen is deposited at the wound. But this can leave bad scar tissue, which will be surgically removed. If the first operation was good, this is not necessary.
So yeah. NSAID's are vital in recovery from inflammation.
@Post-Ironic feel free to correct if i'm wrong
Seriously Dukac, i'm gonna try to explain the situation again, please read this carefully, cause you are wrongly interpreting it.
When you exercise, you create microtrauma in the muscles, tendons and ligaments. The body has a natural response to recover from this. Because of structural differences, the natural recovery of tendons&ligaments, versus muscles is completely different in speed and mechanism.
Muscles :
Muscle trauma will release various molecules called Receptor tyrosine kinases (RTKs) that bind to the IGF1-R, and thus creating IGF-1. This is by far the most potent signalisating molecule for triggering protein synthesis. Because of the muscle trauma, calcium that is normally stored in the smooth ER, will accumulate in the muscle. This calcium will act as an activator for various proteases that break down muscle protein, which causes inflammation, this inflammation is the pain that is felt from non hypertrophy muscle training. This inflammation is an issue, because it will slow down the protein synthesis and slows down the recovery. However, this inflammatory phase is very short for a conditionned athlete. Most importantly, the amount of inflammation is directly proportional to the amount of muscle trauma and does not increase over time. Your muscle will be performing less if it isnt recovered enough.
Tendons and ligaments are mostly made from collagen. Very strong substance. At low stress, they arent good at transferring loads, but as they get more stressed, they become stiffer and transfer the muscle's force MUCH better. Tendons grow in function of the muscle, but the mechanism is much slower. Microtrauma in tendons causes tendocytes to increase expression of IFG-1. However to do this, you need to put a significant strain on them, because collagen is that strong. (this is vital in strenght training. volume builds muscle, but you need to go 80%+ of your maximum to create better tendons, and you need frequency to max out your natural recovery of all of this).
1) When the tendon receives microtrauma however, inflammation of the tissue occurs because inflammatory agents (neutrophils, macrophages and monocytes) will move to the damaged area's and clean the scarred tissue by phagocytosis, inducing an inflammatory responce. So you'll be having slightly inflammated tendons.
2)Then tendon fibroblasts will start repairing the zone by collagen synthesis and depositing this at the wound site. For strenght athletes, this is consistantly happening. So you get consistant inflammation, when it builds too much, you start to feel pain and decreased tendon function. this is overtraining.
3) Then comes the final step of remoddeling. the repair tissue changes to fibrous tissue with the highest stiffness and tension strenght.
The proces duration depends on the amount of trauma. For training induced microtrauma, its about a4-6 days. When you tear off a ligament like marchisio, 1) takes a few days, 2) takes 6 weeks and 3) takes another 10 weeks.
The big issue with training here is that you need to push 85% or higher maximum strenght to force microtrauma, but to make progress you need to keep it continiously going. When making progress, this leads to increased inflammation which will result in acute inflammation. (
1) When the tendon receives microtrauma however, inflammation of the tissue occurs because inflammatory agents (neutrophils, macrophages and monocytes) will move to the damaged area's and clean the scarred tissue by phagocytosis, inducing an inflammatory responce. So you'll be having slightly inflammated tendons.
2)Then tendon fibroblasts will start repairing the zone by collagen synthesis and depositing this at the wound site. For strenght athletes, this is consistantly happening. So you get consistant inflammation, when it builds too much, you start to feel pain and decreased tendon function. this is overtraining.
3) Then comes the final step of remoddeling. the repair tissue changes to fibrous tissue with the highest stiffness and tension strenght.
The proces duration depends on the amount of trauma. For training induced microtrauma, its about a4-6 days. When you tear off a ligament like marchisio, 1) takes a few days, 2) takes 6 weeks and 3) takes another 10 weeks.
The big issue with training here is that you need to push 85% or higher maximum strenght to force microtrauma, but to make progress you need to keep it continiously going. When making progress, this leads to increased inflammation which will result in acute inflammation. (
As seen in the spoilored explenations above, muscles, ligaments and tendons that recover naturally from training, will be slightly inflammated, and in tendons this can build up. This inflammation will decrease the natural recovery from training. When taking NSAID's, this inflammation caused by training will be kept on a minimum, so the natural recovery will be at its best speed.
When you tear something, it will take 4-6 months to recover. However, the recovery system works in the same way. First the ligament or tendon is reattached. step 1(see second spoiler) will clean up all necrotic tissue, causing inflammation. THis step occurs in the hospital, so the patient will receive intravenous NSAID's to controll this . Once past the worst inflammation response (your knee is swollen as fuck), you can go home and will be prescribed with oral NSAID's for some weeks. After x weeks, a docter will examine your scar tissue. In step 2(see second spoiler), we see the collagen is deposited at the wound. But this can leave bad scar tissue, which will be surgically removed. If the first operation was good, this is not necessary.
So yeah. NSAID's are vital in recovery from inflammation.
@Post-Ironic feel free to correct if i'm wrong
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