Once again:
Szczesny
Cancelo, Bonucci, Chiellini, A. Sandro
Bernardeschi, Can, Matuidi, D. Costa
Mario/Dybala, Ronaldo
Mandzukic and Cancelo would also act as backups for the wings. Plenty of games to be played for both Dybala and Mandzukic.
Can there instead of Pjanic obviously because of balance. In a two-CM system, it has to be Can-Matuidi, otherwise midfield is too light.
Based on our heat maps, we exclusively attack down the flanks and rarely attack through the middle, yet don't play our wingers. Three subpar CMs + three strikers who don't defend...that neither helps with defense nor attack. All it does is make the team unbalanced and play poorly.