Im a bit worried, Roma has the best midfield in Italy probably, Salah has caused us problems in the past and we are just getting accustomed to new system and players returning from injury. Id take a draw here
I think their midfield can be easily controlled, because they are not dynamic enough, bar Nainngolan who plays AM, and I believe that Marchisio can easily deal with him when we are defending. The only problem I see is their left hand side paying against our right side of the team, where we have Lichtsteiner and Khedira, who are both slow as fuck, with Lichtsteiner being really poor in addition (looks like he doesn't give a fuck anymore). The solution may be that we switch Lemina's and Khedira's playing positions, so that Khedira plays on the left side of our midfield, and Allegri orders Lemina to press the fuck out of Strootman, with Mandžukić constantly applying pressure on Emerson, in order to cut off the supply for Perotti, then Licht will have an easy job.
I also believe that Džeko could be taken out of the game by both Rugani and Chiellini, and of course their right side of the team should be relatively easy to deal with, The only player going forward will be El Shaarawy, because Rudiger plays RB, and he really shouldn't be a threat.