Though I don't think happiness or tranquality you can get it just by wanting.
Those two things I think are incompatible with todays technocratic world, you will have to at one time or another try to go back to the opposite side of technology in order to achieve them.
The whole concept of technology always leaves you dry, you always have the next step, and as long as you have it you won't be really happy or tranquil, you will always look into the future this way, not to mention material things never bring you lasting happiness. As some chinise smart dude wrote - depressed you are when you live in past, anxious when you live in future, and tranquil when you live today.
If that is really the most important things in life my honest advice would be not to so focused on tech and science. Rather try to look for balance and use science and spirituality accordingly not one or other for every situation. You can't cook food with faith and you can't cure a broken heart with science.