Physical or psychological? As long as you don't make it a habit you should be fine with party drugs like E, LSD, shrooms etc., I would stay away from anything that is habit forming like coke tho .
E is cheaper, lasts much longer, is more enjoyable and less addictive. Other than Cannabis I'm not into drugs anymore but I will always pop E when its around.
Settling in my new project... reading documents has to be the most boring thing known to man... i'd rather watch paint dry...
wats up fireman... wats up desi bratha...