Deadpool is virtually unkillable (as I suspect are other Marvel superheros, I'm not really that much into that so don't know that much about them), but the Super Sayans are otherwise clearly more powerful.
No one would really be able to exterminate each other.
it's not only that he's unkillable, he can travel through dimensions. he can even break the 4th wall, which means all he has to do is write a comic book about him beating goku or giving himself more powers than goku. you can't fuck with deadpool.