If Chiellini gets rested in this game, which he should, then Rugani should replace him in the XI, not Padoin. With Cuadrado back, we can easily go back to the Zona Mista.
-----------Buffon
Rugani Bonucci Barzagli
------------------------Evra
---Khedira Marchisio Pogba
Cuadrado
----------Dybala Morata
Or Barzagli in his usual terzino destro role and Rugani in the middle. I'd feel safer with Barzagli in the middle if Rugani can play terzino destro.