Estigarribia has a style way to wide to play in the center. At most, it should be Pepe there.
Pepe - Pirlo - Vidal
Vuci - Matri - Estiga
We'd be putting one more hardworker in the middle and another one against Maggio. Our most creative force upfront would strike from the right as well, which I think it's where they're more vulnerable. Could work, I guess. Better than put another defensive midfielder on the pitch and lose one vital man in the box.