4312: midfield of poulsen, marchisio and sissoko. Diego for behind the strikers of DP and immobile. Perhaps that's best so DP isn't by himself up there. No way should u leave him alone.
I think we saw last match what effects playing an injured player can have on the team. Amauri is not fit don't play him, he has not been lighting up Serie A so I'd rather he gets time on the bench. I think playing DP alone up front can work if we offer the correct support, he has 3 players who will always be close by and granted we keep the ball on the deck I think it has a good chance of being a sucess. Look at Valencia with Silva,Mata and Pablo and Villa and look how that works out. If you have movement and play the ball on the ground then it should not be a problem.