It won't be easy finding the right formation. Dybala and CR7 seems like a weird mix, as does Pogba with CR7. With Pjanic it could work if you put a Vidal type next to the two of them.
Dybala risks being sacrificed I agree.
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Yeah it would be difficult:
In order to play them, Ronaldo would probably have to play wide left. Or with Dybala playing as a withdrawn forward, while costa plays as a traditional winger. And yeah, you'd likely need Matuidi to play. Or at least, Can. Bentancur is not athletic enough IMO. Khedira not defensive enough.
So something like:
Ronaldo (Free Role) - Dybala (#9 role) - Costa (Inverted Winger)
or
Costa(Winger)-------Ronaldo(#9 Poacher)-
-----------------------------------------Dybala-(Link up Role/Secondary Striker)----------
MF could either be: Pogba-Can-Pjanic or Pogba-Pjanic-Matuido IMO.