Khedira was too tired, it was very evident. Yes, Sturaro was pretty bad tonight, but he bailed us a few times before.
He's obviously no Khedira, or Vidal, but he'll grow.
The sub that really did us the most harm has to be Morata-Mandzukic. It's because we lost all of our attacking threat when Morata went out because we were only really threatening from counter attacks, and Morata showed how dangerous he is when played like that.
He was tired though and brining on Mandzukic made sense as we were 2-0 up and he's basically a defender now.