Higuain isn't a bad choice for MVP, as he is (obviously) the top scorer, could be relied on in pretty much every game, played the whole 90 minutes almost every game and surprisingly turned up in some crucial crunch games (Fiorentina, Monaco, Napoli etc). Dani Alves has been a man possessed lately but was injured a good chunk of the season.
For me though it's gotta be Mandzukic, as the system change to 4-2-3-1 relies almost solely on his work rate, not to mention he also runs for 90 minutes in almost every single game nonstop. He's also brought in some crucial goals, assists and performances against the likes of Barcelona and Monaco. Don't remember him really having a bad game this season.
Bonucci is another player that has had a fantastic season, has scored some big goals and could be relied on in pretty much every game.