Just finished my first season and I'm having excellent results alternating between custom 4-1-2-1-2 and 4-1-3-2 formations
here is my starting lineup as well as the alternative 4-1-3-2 (i've also just purchased Alex Sandro from Porto but the deal hasnt been finalized yet.) As you can see I was able to win Serie A quite comfortably and these results are from before i had signed Ter Stegen, Verratti, and J. Rodriguez. Buffon, Pirlo, and Marchisio fit their roles respectively and the rest of the lineup was the same.
Dominates posession, even in europe, and defensively it is rock solid the Biggest issue i've faced so far is that Tevez and Llorente waste so many chances that should really be goals.