We struggled in Turin because Lokomotiv had everyone behind the ball. This time it's a must win for them if they want to stay in contention for the CL knockouts. Unless they score early and make it a similar match as the one in Turin, we should have much more space than we're used to.
A win here secures the CL knockouts but doesn't secure top spot. We'll still have to beat Atletico for that (or if we play a draw with Atletico, we might have to beat Leverkusen in Germany in the last round). And top spot is important this year, because the favorites will likely win their groups and it's important to avoid them in early knockouts (City, Barcelona, PSG, Bayern, probably Liverpool too). We will likely qualify for the knockouts in round 4 already, but for the top spot we might wait until the last round.