It seems pretty clear that there are players better suited to the 3-5-2 than one of Prandelli's back four variants. Bonucci is one of them, and Maggio is another. Those two would play in the typical Juve back five, probably with Balzaretti.
The lack of a really good authentic right back is a problem. I'm not sure how De Sciglio would do there but he's right footed and perhaps could make a side swap just as Zambrotta did. Italy have far more good options at left back, and maybe even Ogbonna could work his way into that role.