Honestly if we are pairing Dzeko with Ronaldo, we need a pacy high quality winger on the other side to give that balance to the attack. I'm not sure it is going to work with Dybala on the other side.
In Dzeko, Dybala and Ronaldo, we also effectively have 3 players who dont track back so if you are going to accommodate all of them together, we need midfield tanks to support them and we don't have them. We also need highly athletic and competitive fullbacks who can provide the width and be good defensively as well and we don't have THAT either.
Edit : Playing Kulu instead of Dybala would make the attack more balanced however