Our defense was shaky from the start of the season, If we didn't concede lots of goals, that's because we have the best goalkeeper of the world. with that average defense we were lucky not to concede a lot, but when you lose all of them, and you depend on Molinaro and Boumsong and leave them alone and focus on attacking, well, this is not Empoli, they even could score more than 3, and we are not that great to score another 5 against a team like Sampdoria. If you had creative midfielders like Diego or VDV, I would tell you go take the risk, you know our midfield too that they are not creative enough, if you make them weaker, by reducing another player, I am afraid we can't even score a goal.
I would stick with 4-4-2, or use 4-5-1, or 5-4-1 with fats counter attacks. I don't care what formation we will play, but one thing I am sure is that we need to play next match with 4 midfielders at least!