Radja and Keita played all of their matches so far, we should have the advantage of it.
Yeah, has to be a chance to get at Roma late on.
As Garcia said after the City game:
"...we suffered in the last 10 minutes because we’ve been forced to play the same men in central midfield and defence for weeks."
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Complicated tactical match-up for Juve if they try to play their normal game as it'll be very hard for Juve to find the balance with the wing-backs against the front three of Roma.
Roma are one of very few teams in world football just now that Juve cannot be sure of winning the midfield against. Without the platform of being dominant in midfield, as Juve usually are, you really do have to be much more aware of the attacking strengths of the opposition.
Of course, you could simplify matters and just match-up all over the pitch and try to turn the game into a bunch of one-on-one confrontations rather than so much of a tactical battle:
Bonucci stays spare as sweeper
Caceres-Iturbe
Chiellini-Gervinho
Marchisio-Totti
Lichtsteiner-Cole
Vidal-Pjanic
Pogba-Nainggolan
Asamoah-Maicon
Tevez-Keita