I think playing Vidal as CB is a big mistake. I fear that he will end up commiting some stupid fouls that will cost a goal and/or a red card, BUT the worst part is that he won´t be able to use all his energy in midfield and press/stress the Genoa midfield. Marchisio can´t do that, and Marrone is not that type of player.
Vidal is our best weapon against counter-attacks IMO and if we fail to win the midfield battle, then we will loose vital points again.
Also, in these situations when all our defence is unavailable -
lets give youth a chance, something I personally have seen much, much, too little in my 15-ish years as Juventino!!
I expect a tough game with higher than usual tempo, which is why Giac should be preferd to lazy Vucinic.
My line-up would be this, (even though we all know Conte has his favorites, so it is not going to happen)
Ohh, "Casper" needs some time on the "tribuna sud" which is the tribuna that the sun is facing on afternoons - if he is lucky, he might get some colour by catching enough sunrays - making him more visible on the field

- hence I prefer Marrone.
Buffon
Licht-Caceres-Guano-De Ceglie
Vidal-Pirlo-Marrone
Pepe-Matri-Giac