I'd give it a go to players who didn't have many chances this year. Also the starters should rest as some kind of prize for winning the league.
We could also make a few experiments. Try 433 again. Asamoah as a midfielder, Isla as a right winger, Giovinco as a left winger.
Storari - Peluso, Caceres, Bonucci, Padoin - Marrone, Asamoah, Giaccherini - Isla, Giovinco, Matri (Quagliarella)