So you think that Pogba, Vidal, Pirlo (haven't even included Marchisio at this stage, as only three fit in midfielder, or Asamoah) would cut down to say, 30 league games each, so Nainggolan can play 24? It's possible but improbable.
If you add all the midfielders into the mix you are probably looking at 25-28 games each, for Serie A.