Pepe has simply had his hands full covering a whole flank, on either side. He doesn't have the time to play offensively, but when he did he misplaced the crosses.
Martinez looks rusty, but at the same time he looks like a player with a nice touch and good dribbling ability. I'd like to see more of him, he has barely played so far. That doesn't take away he's wasted too many balls and has barely created a thing.
Marchisio is just pretty quiet, but usually he can be a silent force in midfield, calm and collected, but he's been wasting possession too much. Not great.
Melo has been a monster so far.
I'd like to see more dynamic forwards though. Diego and Amauri would make a difference to this team, this formation. But so would Krasic, Motta, Aquilani and possibly Bonucci even. We're not playing our starting 11 tonight.