Cuadrado is better when he does not have the ball. We have to adapt the team away from him a little bit. And we have to encourage him to move away from his comfort zone which is to drift into space and stand still until he gets the ball, at which point he initiates a dribble against 4 players.
That moment when he ran the line like a train and Khedira put the ball over the top is the exact way to use Cuadrado. Let him move towards the net without the ball and put the ball there for him at the end.
It's a more effective tactic to have Pogba, Marchisio, Dybala or Morata with the ball and use Cuadrado more as a classical winger IMO. Trying to dribble through Italian defences will never work.
If he even just makes off ball runs like Lichtsteiner he will be more effective. Since obviously he can cross, shoot and dribble better at the conclusion.