I think thats way too attacking, thats 4 "strikers" who won't really help out in defensive duties. I am guessing that Honda will play upfront like he did with Japan.
And if Pirlo is one of the midfielders, then you get another guy who doesn't help defensively.
The Dutch were playing something similar, but Kuyt was doing more work than Dinho does and Pirlo's job in Milan was done by van Bommel/ de Yong in Holland.
Or one could use Spain as a comparison, but you can't compare the workrate of Xabi with Pirlo, and the Spaniards play defense with strong possession football, which Milan can't do. Also, Spanish defense is younger and better than Milan's defense. As is the goalkeeper.
It would still be interesting to see how will this work in serie A. That's a huge potential in attack and even if this team might be destroyed by Inter, overall they might collect enough points against the smaller teams to win the scudetto.