He won't use a new formation, and even though i like 4-2-3-1, this is not the game to experiment.
I think it i depends on DP. If he wants to use him it'll be 4-3-1-2 if not, then it could be 4-3-2-1 with candreva beside Diego and stealth in front the defense with Sissoko, Melo and Marchisio.