Well then we would have 2 players leaving for African Nations Cup at the start of next year.
The cup lasts 20 days. (the last one was from January 20- February 10)
Since the players will probably be released at least a week earlier, it's about a month, or some 4 rounds in serie A.
Ok, if Mali won't make it to the final or the semis then it's gonna be 3 rounds in serie A.
It isn't too much, but it could prove to be decisive. We all saw what happened when we were without Sissoko this year.