I wouldn't mind signing Cuadrado, but it would not mean that we don't need a trequartista.
Cuadrado would ultimately allow us to play a 4-3-3. He could play on the left, with Dybala on the right.
Mandzukic would make room for the other two, where Dybala and Cuadrado would play as advanced wide attackers. Cuadrado played on the left/central attacking positions multiple times with Fiorentina and was effective, and there is no reason Dybala couldn't play as a wide attacker on the right who can cut in and shoot with his left.
If this was done, I'd still want to add attacking midfielder. Cuadrado isn't creative, and I'm fearful that acquiring no creative player could make our build up play very frustrating.