We can play 4-2-3-1 only if Camo is fit.
Against Napoli we saw how important Camo is for this 4-2-3-1 formation. When he got injured Ciro simply just swapped him with Tiago, but Tiago is no Camo nor even a winger, and Napoli started to dominate our right sight. That eventually made also Grygera look worse. When Camo was on the pitch, we saw how nicely Camo and Grygera where combining together.
Of course other players are also important, but Camo is extremely important for this formation, since his our only natural RW. And it showed today.
Anyway, when DP is back, we will drop this formation, its inevitable.