Higuain is way better in a properly set team as a goalscorer, but is nearly useless if the team is disfunctional...also chokes on important games
Mandzukic works in any team because of his physical attributes, but is nowhere near as lethal as Higuain, proven by sheer numbers. He shines in important games tho.
I would prefer Higuain 10 of 10 if he has a proper set up behind him, but since we got Ronaldo, Higuain is surplus at this point. Mandzukic would be more useful for those physical games which we will need to rest CR7, and is cheaper.
Higuain out obviously