I'm currently in Season 2, got 13 straigt wins, including a 7-0 win against Roma and a 9-1 win against Fenerbahce
Altho I have to admit I cheated a bit. I find the players I want, go into a real time editor, make their contracts expire in a few days, make Juve their favourite team and then sign them
Altho I then add the amount I think the teams deserve for every player. For example, I raised Parma's budget for 20 million pounds for Adriano.
But I had an even better team before, without cheating.
At the start of season 5 I had this team:
Buffon, Cech
Tudor, Lucio, Bonera, Mexes
Ronaldinho, Nedved, D'Allesandro, Joe Cole, Diego, Kaka, Farnerud, Kallstrom, Arteta, Brighi,
Del Piero, Trezeguet, Tevez, Robinho, Le Tallec, Cavenaghi
I probably forgot a few players as it was a few months ago.
In 4 seasons I won the Serie A twice, Coppa Italia twice and the CL 3 times, losing the last final against Bayern.