Pretty defensive team that Lazio are expected to play:
Marchetti
Konko-Biava-Dias-Radu
Ledesma
Candreva-Brocchi-Hernanes-Gonzalez
Klose
Radu in for Lulic and Brocchi in for Mauri, compared to their regular side.
Juve are going to have to play very well to open up space in this game, particularly without Pirlo.
This Lazio team does an awful lot of things well, particularly their midfield. They understand how to position themselves and how to hold possession, which means that it is very difficult to build up a sustained period of pressure against them
Their main weakness defensively is that they are consistently vulnerable on set-pieces, which is something Juve should be able to exploit. Lazio's CBs are also slow and struggle when defending in an open game, but, as I said, Lazio's midfield is very good at preventing a game becoming open.
I'm predicting 1-0 to Juve, probably with a goal from a set-piece.