Yeah I edited my post re Dybala
I checked out the heatmap for Zaniolo's best games according to whoscored and they all appear to be when he plays RW/RM, though he does seem to come centrally a bit
I'm not sure I see either of them having the attributes needed to play as a CM* and/or their best attributes would be wasted there. Though I've seen less of Zaniolo and am judging him from highlights, comp videos and stats

* especially a Sarri-specific type of CM
I just don't see both of them lining up with Ronaldo and Dybala. Maybe with another coach that would use a 4-2-3-1, but still, the left wing would be exposed defensively.