Selling Matri and replacing him with Nani is a no-brainer.
We'd be able to play any formation. Also we could try a 3-4-2-1 when trailing or pressing teams.
Barzagli-Bonucci-Chiellini
Lichtsteiner-Vidal-Pogba-Asamoah
Tevez--------Nani
Llorente
All you're doing is taking the 3-5-2 and subtracting the regista in favour of a second striker/winger really. Bonucci could handle the ball mostly like he does now but we'd be much more unpredictable in our movements with Tevez and Nani able to drift central to receive ground balls or to drift in behind the defense or to the corners.
I really really like Nani because he can play any style. He is great on counters because of pace but he's a rare player that can actually slow down around the box and provide intelligent passes and create combinations which is essential in Serie A.