Changing the formation for Inter doesn't sound like a good idea.
I'd start Kostic and Openda for missing Cambiaso and Chico and stick to the main formation. Mario didn't look too good on the left last time either.
We want to have players that thrive in 1vs1 situations. Yildiz, Openda, Chico and Zeghrova are all capable of beating their marker creating an advantage.